Methylphenidate is a CNS stimulant medication that is used for the treatment of attention deficit hyperactivity disorder and it is also used for narcolepsy. It is available under Ritalin, Concerta, Delmosart, Equasym, etc. Modafinil is also a central nervous system stimulant that is available for the treatment of narcolepsy, sleep apnea, and shift work disorder. Its brand name is Provigil. In this article, you will learn about the differences between Modafinil and Methylphenidate and their similarities.
Modafinil vs Methylphenidate For ADHD
Methylphenidate is an FDA-approved medication for the treatment of ADHD. Modafinil may also be effective for the treatment of ADHD but the FDA has not approved this medication for the treatment of ADHD. However, according to studies, researchers say that Modafinil can be as effective as Methylphenidate. Currently, Modafinil can be prescribed as an off-label medication for ADHD.
Modafinil & Methylphenidate: Dosage
You should take the dosage of Methylphenidate and Modafinil according to your prescription. Changing the dosages of these medications on your own without the consultation of the doctor may be harmful to you. You should also not share the same dosages of these medications with your family members or friends because the dosages are different for everyone and depend on several factors. Sharing the same dosages of these medications may lead to an overdose and may cause the following symptoms.
- Confusion
- Fast heartbeat
- Fever
- Hallucinations
- Tremors
- Headache
- Muscle pain
- Dry mouth
- Palpitations
- Sweating
- Fainting
- Blurred vision
- Abdominal cramps
- Diarrhea
- Nausea
- Vomiting
- Agitation
- Rapid breathing
- Restlessness
- Aggression
- Dizziness
Warning And Precaution of Modafinil vs Methylphenidate:
Every medication has certain conditions for its effective use and for your safety, you should know about these conditions. You should follow the below-mentioned facts to use Modafinil and Methylphenidate effectively.
- If you or your family member has a history of mental issues then you should discuss it with the doctor before you start taking Modafinil or Methylphenidate.
- In case of liver disease, there can be issues with the metabolism of these medicines, you should inform your doctor about this condition so that the doctor can determine the dosages of Modafinil or Methylphenidate according to your condition.
- You should notice that if you are facing any allergic signs when taking these medications, in case of an allergic reaction, stop taking the medication and consult your doctor.
- In pregnancy or the case of a breastfeeding mother, you should avoid taking Modafinil and methylphenidate because it may cause issues for your newborn.
Side Effects of Modafinil and Methylphenidate:
If Modafinil or Methylphenidate is not taken properly, according to the prescription then it may cause some side effects. Some side effects of these medications are mild and may fade away with time but some of the side effects are serious and you may need medical assistance to deal with these side effects.
Some common side effects between Modafinil and Methylphenidate:
- Headache
- Anxiety
- Diarrhea
- Dizziness
- Chest pain
- Sleeping issues
- Confusion
- Skin-related issues (like rashes and itching) In these cases you can search for how to get rid of skin rashes to prevent these types of skin issues.
Other side effects of Modafinil:
- Nausea
- Changes in mood
- Shortness of breath
- Sour stomach
- Tremor
- Mental disorder
- Nervousness
- Rhinorrhea
- Back pain
- Xerostomia
- Mouth ulcer
- Constipation
- Heart problems
- Heartburn
- Reduced appetite
Other side effects of Methylphenidate:
- Psychomotor agitation
- Palpitations
- Abdominal pain
- Melena
- Bleeding gums
- Fear
- Vomiting
- Decreased weight
- Seizures
- Trouble sleeping
- Diplopia
- Chills
- Cough
- Dark urine
- Drowsiness
- Hypertension
Withdrawal Symptoms:
If the higher dose of these medications is taken for a longer duration then you may face withdrawal symptoms. If you are thinking of quitting Modafinil or Methylphenidate after a long duration then discuss it with the doctor and stop correctly taking this medication so that you can minimize the risk of withdrawal symptoms.
Withdrawal symptoms of Modafinil:
- Low mood
- Anxiety
- Insomnia
- Lethargy
- Sleepiness
- Headaches
Withdrawal symptoms of Methylphenidate:
- Aggression
- Sleep disturbances
- Mood swings
- Cravings for the drug
- Psychosis
- Paranoia
- Anxiety and depression
- Hunger or increased appetite
- Inability to concentrate
- Excessive sleepiness
- Fatigue
Modafinil vs Methylphenidate: Drug Interactions
When you are taking Modafinil or methylphenidate, ask your doctor before You take any other over-the-counter or prescription medications because their interaction may impact the working function of these medications or increase the risk of side effects of Modafinil or Methylphenidate.
Methylphenidate:-
- Atomoxetine
- Lithium
- Procarbazine
- MAOIs (Carbex, Eldepryl, Marplan, Nardil)
- Other stimulant medications for attention disorders
- Medicines for blood pressure, heart disease, irregular heartbeat
- Medications for depression or anxiety
- Medications for seizures (carbamazepine, phenobarbital, phenytoin)
- Cold or allergy medications
Modafinil:-
- Amphetamine
- Methylphenidate
- MAO Inhibitors (Nardil, Parnate, Marplan)
- Procarbazine
- Antifungal medicines (itraconazole or ketoconazole)
- Phenobarbital
- Birth control pills
- Carbamazepine
- Diazepam
- Medicines for depression or anxiety
- Phenytoin
- Propranolol
- Triazolam
Conclusion
Modafinil and Methylphenidate, both are available for the treatment of sleeping-related issues and ADHD. Modafinil is used as an off-label medication for ADHD because the FDA does not approve it for ADHD. When it comes to deciding which medicine is better for you, it depends on different factors and after assessment, only the doctor can determine the best medicine for you. So you should never take these medications as an over-the-counter pill because it may also cause severe side effects.
FAQs (Frequently Asked Questions)
Is Modafinil Similar To Methylphenidate?
Methylphenidate is used for ADHD and the FDA has approved this medication but Modafinil may be used as an off-label medication for ADHD. Methylphenidate works by increasing the level of Norepinephrine and Dopamine in the brain while the working of Modafinil is unknown.
Why is Modafinil not approved for ADHD?
Modafinil is not prescribed for ADHD because the FDA has not approved this medication for the treatment of ADHD. The working mechanism of this medication is unknown and there is a lack of studies regarding Modafinil related to ADHD. The effectiveness of Modafinil for ADHD is under discussion till now.
Does Modafinil Feel Like A Stimulant?
Yes, Modafinil is a central nervous system stimulant and after taking this medication you may feel the same as you feel after taking other stimulant medications.
Does Modafinil Increase Dopamine?
The actual working function of Dopamine is unknown but it is said that it blocks the dopamine reuptake and increases its level in the brain instead of draining it.
What Happens If I Take Methylphenidate But I Don’t Have ADHD?
People take this medication to enhance their performance in studies or at work. After taking this medication you may feel more enthusiastic but it also has some side effects.
Who Cannot Take Methylphenidate?
A person with a history of depression, mania, or other mental disorders, kidney disease, or liver disease, should be careful with the use of methylphenidate.
Does Methylphenidate Give You Energy?
Yes, you feel energetic after taking Methylphenidate, as it is a stimulant and creates an awakening effect.